Papp D^, Hernandez L.A.^, Mai T.A.^, Haanen T.J.^, O'Donnell M.A.^, Duran A.T.^, Hernandez S.M.^, Narvanto J.E.^, Arguello B^, Onwukwe M.O.^, Mirkin S.M., Kim J.C. Massive contractions of Myotonic Dystrophy Type 2-associated CCTG tetranucleotide repeats occur via double strand break repair with distinct requirements for DNA helicases. G3. 2023 Nov 10. PMID: 37950892.
Neil A.J., Kim J.C., and Mirkin S.M. Precarious maintenance of simple DNA repeats in eukaryotes. BioEssays. 2017 Jul 13. PMID: 28703879
Tsutakawa S.E., Thompson M.J., Arvai A.S., Shaw S.J., Neil A.J., Shaw S.J., Algasaier S.I., Kim J.C., Finger L.D., Jardine E, Gotham V.J.B., Sarker A.S., Her M.Z., Rashid F, Hamdan S.M., Mirkin S.M., Grasby J.A. and Tainer J.A. Phosphate steering by Flap Endonuclease 1 promotes 5’-flap specificity and incision to prevent genome instability. Nature Communications. 2017 Jun 27;8:15855. PMC5490271
Kim J.C., Harris S.T.^, Dinter T.^, Shah K.A., and Mirkin S.M. The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats. Nat Struct Mol Bio. 2017 Jan;24(1) 55-60. PMC5215974
See related press coverage here.
Kim J.C., and Mirkin S.M. Putting the Brakes on Huntington Disease in a Mouse Experimental Model. PLoS Genet. 2015 Aug 6;11(8). PMC4527745
Aksenova A.Y., Greenwell P.W., Dominska M., Shishkin A.A., Kim J.C., Petes T.D., and Mirkin S.M. Genome rearrangements caused by interstitial telomeric sequences in yeast. Proc Natl Acad Sci U.S.A. 2013 Dec 3;110(49):19866-71. PMC3856781
Kim J.C., and Mirkin S.M. The balancing act of DNA repeat expansions. Curr Opin Genet Dev. 2013 Jun;23(3):280-8. PMC3703482
Kim J.C. and Orr-Weaver T.L. Analysis of a Drosophila amplicon in follicle cells highlights the diversity of metazoan replication origins. Proc Natl Acad Sci U.S.A. 2011 Oct 4; 108(40): 16681-6. PMC3189023
Kim J.C., Nordman J, Xie F, Kashevsky H, Eng T, Li S, MacAlpine D.M., and Orr Weaver T.L. Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression. Genes Dev. 2011 Jul 1; 25(13): 1384-98. PMC3134082
^ Indicates student co-author
Neil A.J., Kim J.C., and Mirkin S.M. Precarious maintenance of simple DNA repeats in eukaryotes. BioEssays. 2017 Jul 13. PMID: 28703879
Tsutakawa S.E., Thompson M.J., Arvai A.S., Shaw S.J., Neil A.J., Shaw S.J., Algasaier S.I., Kim J.C., Finger L.D., Jardine E, Gotham V.J.B., Sarker A.S., Her M.Z., Rashid F, Hamdan S.M., Mirkin S.M., Grasby J.A. and Tainer J.A. Phosphate steering by Flap Endonuclease 1 promotes 5’-flap specificity and incision to prevent genome instability. Nature Communications. 2017 Jun 27;8:15855. PMC5490271
Kim J.C., Harris S.T.^, Dinter T.^, Shah K.A., and Mirkin S.M. The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats. Nat Struct Mol Bio. 2017 Jan;24(1) 55-60. PMC5215974
See related press coverage here.
Kim J.C., and Mirkin S.M. Putting the Brakes on Huntington Disease in a Mouse Experimental Model. PLoS Genet. 2015 Aug 6;11(8). PMC4527745
Aksenova A.Y., Greenwell P.W., Dominska M., Shishkin A.A., Kim J.C., Petes T.D., and Mirkin S.M. Genome rearrangements caused by interstitial telomeric sequences in yeast. Proc Natl Acad Sci U.S.A. 2013 Dec 3;110(49):19866-71. PMC3856781
Kim J.C., and Mirkin S.M. The balancing act of DNA repeat expansions. Curr Opin Genet Dev. 2013 Jun;23(3):280-8. PMC3703482
Kim J.C. and Orr-Weaver T.L. Analysis of a Drosophila amplicon in follicle cells highlights the diversity of metazoan replication origins. Proc Natl Acad Sci U.S.A. 2011 Oct 4; 108(40): 16681-6. PMC3189023
Kim J.C., Nordman J, Xie F, Kashevsky H, Eng T, Li S, MacAlpine D.M., and Orr Weaver T.L. Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression. Genes Dev. 2011 Jul 1; 25(13): 1384-98. PMC3134082
^ Indicates student co-author